VERSE CHORUS
When plasmids came into this world Conjugation, Penetration, Consummation
Who'd have thought that they would be Oh that's great
A problem for the doctors De-repress your inhibition
And a research grant for me Find a mate and aggregate
We see them keep on growing Now penetrate the membrane
World-widely they abound Right onto the chromosome
Collecting genes like garbage If you miss you're just a plasmid
And passing them around Try to be an episome!
When I was just a little gene Conjugation, Penetration, Consummation
Upon the chromosome Oh that's great
A plasmid sat down next to me De-repress your inhibition
Said "Don't be a stay-at-home!" Find a mate and aggregate
Excise with me, I have the stuff Now penetrate the membrane
My tra genes are intact Right onto the chromosome
The time has come for you to learn If you miss you're just a plasmid
About the mating act. Try to be an episome!
I am a lively pilus Conjugation, Penetration, Consummation
On the surface of a cell Oh that's great
I have a reputation De-repress your inhibition
As a sexy organelle Find a mate and aggregate
It's my good luck, I'm not Fin+ Now penetrate the membrane
I'm always out to play Right onto the chromosome
When I attach, oh what a match If you miss you're just a plasmid
We have a holiday! Try to be an episome!
I am a special entity Illegitimate recombination, transfor-
Oh happy happy me mation are just two
My life is full of fun and games Of the acts that we do daily
And promiscuity In and out of each of you
Who else can flit so easily We are Nature's way of giving
From one mate to the next Special functions which you'll use
No care about the species To survive the contamination
And even less the sex! In the stuff they call their foods.
A Horny Streptococcus
VERSE CHORUS
A horny Streptococcus Stimulation, titulation
Encultured with a male CIA will turn you on
Exudes her sexy pheromone You'll become a hairy fellow
And leaves a perfumed trail What a joy to gaze upon
He likes her smell, it turns him on It's a positive experience
He sprouts a fuzzy coat For a fecalis male
Once they begin their friends join in Forget it, you Gram Negatives
A gangcoccal Love Boat You're only doomed to fail
I'm losing my stability When you're in a bad position
My vector's in arrears Transposition is the thing
My cop is low, my rep is gone, Look around for a new target
I fear the end is near Grab ahold and move right in
Don't hold me back, I've got to go Though you're needy, don't be greedy
It's clear I have two P Just one copy is enough
My neat repeat provides a seat If you amplify your genome
It's in or out for me You will just Muc up the stuff
I am a binding protein Cut me up and rearrange me
Though my domains are few Up my cop and probe me too
Expose me to a protease If you fuse me don't confuse me
And I'll split into two With another gal that's blue
If you need me for a footprint If you must tinker, add a linker
Just don't disturb my pleats For example, pro X gly
You can have my alpha helix If you prove yourself a thinker
Slip 'twixt my beta sheets I will give you perfect pi
I was just a quiet gene Cut me up and rearrange me
In total self-control Up my cop and probe me too
I hid behind a fig leaf If you fuse me don't confuse me
With my regulation soul With another gal thats blue
Now my partisome is parted If you must tinker, add a linker
And I am in a jam For example, pro X gly
But I don't give a dcm If you prove yourself a thinker
And I don't give a dam I will give you perfect pi
Naomi kicked the meeting off
Her plasmids are just smashing
Then she put her glasses on
And shocked us all b flashing
She impressed us with her super
Com-pa-ti-bi-li-ty
Though she's retiring to Chiswick
She leaves a legacy